Mitochondrial Replacement Therapy, Jewish and Catholic Ethical Perspectives
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Ian Sample, “First UK licence to create three-person baby granted by fertility regulator,” The Guardian, March 16, 2017. https://www.theguardian.com/science/2017/mar/16/first-licence-to-create-three-person-baby-granted-by-uk-fertility-regulator
Ariana Eunjung Cha, “FDA cracks down on company marketing ‘three-parent’ babies,” The Washington Post. August 8, 2017. https://www.washingtonpost.com/news/to-your-health/wp/2017/08/07/fda-cracks-down-on-company-marketing-three-parent-babies/?utm_term=.930f28cd5fc9
Jessica Hamzelou, “World’s first baby born with new ‘3 parent’ technique,” New Scientist, September 27, 2016. https://www.newscientist.com/article/2107219-exclusive-worlds-first-baby-born-with-new-3-parent-technique/
Sara Reardon, “Reports of ‘three-parent babies’ multiply.” Nature, October 19, 2016. https://www.nature.com/news/reports-of-three-parent-babies-multiply-1.20849
The three methods of Mitochondrial Replacement Therapy are pronuclear transfer, maternal spindle transfer, and nuclear genome transfer; https://www.sciencedaily.com/releases/2017/04/170403083119.htm
Don P. Wolf and Shoukhrat Mitalipov, “Mitochondrial replacement therapies can circumvent mtDNA-based disease transmission,” Cell metabolism 20 (2014): 6–8.
Cf. PIUS XII, Address to the Second World Congress in Naples on Human Reproduction and Sterility (May 19, 1956); AAS 48 (1956), 470; PAUL VI, Encyclical Letter Humanae Vitae, 12; AAS 60 (1968), 488–89; Congregation of the Doctrine of the Faith, Instruction Donum Vitae, II, B, 4–5: AAS 80 (1988), 90–94 and Instruction Dignitas Personae,16 (2008).
Congregation of the Doctrine of the Faith, Instruction, Dignitas Personae 14, cites the statistic of the number of embryos sacrificed, even in the most technically advanced centers for artificial fertilization, as hovering above 80%.
Simon Cladwell, “Three-parent baby law makes human life disposable, says bishop.” Catholic Herald, February 4, 2015. http://www.catholicherald.co.uk/news/2015/02/04/three-parent-baby-law-makes-human-life-disposable-says-bishop/
Renée Mirkes, “Three-Parent Embryos: Gearing Up for the US Debate,” The Catholic World Report, March 12, 2015. http://www.catholicworldreport.com/Item/3745/threeparent_embryos_gearing_up_ for_the_us_debate.aspx
R.M. Tendler and John D. Loike, “Mitochondrial Replacement Therapy: Halachic Considerations for Enrolling in an Experimental Clinical Trial,” Rambam Maimonides Medical Journal 6, no. 3 (2015).
Sarah Fogleman, Casey Santana, Casey Bishop, Alyssa Miller, and David G. Capco, “CRISPR/Cas9 and mitochondrial gene replacement therapy: promising techniques and ethical considerations,” American Journal of Stem Cells 5, no. 2 (2016): 39.
Avraham Steinberg and Fred Rosne, Encyclopedia of Jewish Medical Ethics. Jerusalem (Israel: Feldheim Publishers, 2003), 1–29.
John D. Loike, M.D. Tendler, and Ruth Fischbach, “Jewish views on the beginnings of human life and the use of medical intervention to produce children,” American Journal of Bioethics, 9 (2009): 45–47.
Rambam, Hilchot Rotzeach, chap. 11–12 and Shulchan Aruch Choshen Mishpat, chap. 426.
Rambam, Hilchot Deiot, 4:1
Lucía Gómez-Tatay, José M. Hernández-Andreu, and Justo Aznar, “Mitochondrial Modification Techniques and Ethical Issues,” Journal of Clinical Medicine 6, no. 3 (2017): 25.
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